How Should Prednisone be Used ?

Prednisone comes as a tablet, a solution (liquid), and a concentrated solution to take by mouth. Prednisone is usually taken with food one to four times a day or once every other day. Your doctor will probably tell you to take your dose(s) of prednisone at certain time(s) of day every day. Your personal dosing schedule will depend on your condition and on how you respond to treatment.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take prednisone exactly as directed. Do not take more or less of it or take it more often or for a longer period of time than prescribed by your doctor.
If you are taking the concentrated solution, use the specially marked dropper that comes with the medication to measure your dose. You may mix the concentrated solution with juice, other flavored liquids, or soft foods such as applesauce.
Your doctor may change your dose of prednisone often during your treatment to be sure that you are always taking the lowest dose that works for you. Your doctor may also need to change your dose if you experience unusual stress on your body such as surgery, illness, infection, or a severe asthma attack. Tell your doctor if your symptoms improve or get worse or if you get sick or have any changes in your health during your treatment.
If you are taking prednisone to treat a long-lasting disease, the medication may help control your condition but will not cure it. Continue to take prednisone even if you feel well. Do not stop taking prednisone without talking to your doctor. If you suddenly stop taking prednisone, your body may not have enough natural steroids to function normally. This may cause symptoms such as extreme tiredness, weakness, slowed movements, upset stomach, weight loss, changes in skin color, sores in the mouth, and craving for salt. Call your doctor if you experience these or other unusual symptoms while you are taking decreasing doses of prednisone or after you stop taking the medication.

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Treat Nephrotic Syndrome with Hormones

Hormone is commonly used in treating nephrotic syndrome(NS) in western medicines and is often chosen by patients at the early stage of treatment.The curative effect of hormones in treatment process should be analyzd from the following aspects.

Primary treatment stage.
The curative effect of hormones has something to do with the dose. At the first,the dose should be large enough to alleviate the condition quickly. The dose of prednisone(pred) for the adults is 1mg/kg,as for the individual patients,the dosage can be increased to 1.5mg/kg. It is reported that the dose of prdnisone for children aging from 2 to 6 years old should be 2～2.5mg/kg.The younger the children are ,the greater the pred will be. It is worthwhile to note that the daily consumption of hormone less than 80mg is better. It is better to take the hormone in the morning.
The stage of reduction treatment
After about 8 weeks of using large dose of hormones,the dose should be reduced to 10% of the previous amount,that is 5mg for the adults. There are three points should be noted. First,if patient’s condition is not improving or even becomes worse after 8 weeks,excluding the factors such as infections which may affect the curative effect,continuous medication may be of no avail(hormone-ineffective type),the patients should reduce the consumption of hormone quickly in order to stop taking bills temporarily. If it is allowed,renal biopsy should be taken for a further and detailed check.
Second,if the symptoms such as urine protein reduced more than a half and swelling is alleviating,then amount of hormones can be reduced to 0.5mg/kg for the adults and 1 mg/kg for the children. The hormones can be taken every two daysin the morning.
Third,if the patients recover quickly because of the large dose of hormones,or the curative effect is seen within 6 weeks,the hormones can be used for another two weeks to consolidate the condition and then reduce the dosage. Generally speaking,the course of hormones is less than 3 months ,the increase of dosage and prolonged treatment should be operated carefully.
Persistent treatment period.For the primary large dose of hormones,some patients may become better and the dose can be reduced to small amount(adults:1mg/kg，children:2～2.5mg/kg) for sis months or longer. During the persistent period treatment,if the patients is in remission,the patients should take the medicines for another four weeks and then reduce the dose gradually till stop taking them.
For the hormone sensitive patients who achieve complete remission,they usually can reduce the dose to the maintenance level,that is,pred 0.4mg/kg,which is the necessary amount for the patients. There is a condition that the patients achieve in complete remission when they use hormones at first ,but the disease relapse in a short period or relapse because of reduction of dose. Under this circumstances,hormones can be used again according to the previous prescription for 12 to 18 months.

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Be careful about the traditional Chinese medicine

Many people thought that the traditional Chinese herbs are mild and has no side effect at all. But some herbs are really have effects and also have side effect for it contains toxin such as aristolochine . According to the medical report the side effect of abuse of the herbs are in a rising way recent years. And what is more the side effect can influence all the systems of the body and the kidney is an organ that suffers a lot.

In 1993, a scholar from Belgium reported that after using a certainweight-reducing aid the kidney failure appears in some cases which causes the attention of the whole world for the herb use.

According to a news report in China, some people thought they got inflamed in the inner body so they choose some herbs. In the early stage the effect is very obvious but later patients will appear symptoms such as tired, anemia , and low appetite. They went to the hospital to check and diagnosed as Aristolochic acid nephropathy.

An old traditional Chinese doctor in Beijing said that he remembered that his grandfather used to eat Gentian purging liver pills to relieve the inner anger of the body. But finally died of kidney failure. In order to live many patients chose dialysis which expanse a lot of money.

In 1988, China promulgated a law of controlling the medical market. The law has made it clearly that some herbs are veneniferous such as flos daturae and unprocessed Fructus Crotonis. Some herbs contain toxin themselves but some herbs get the toxin when planting in the toxin water or soil.

The toxin in the herb can damage the Renal tubular directly or make the kidney short of blood. The patients will suffer blood urine, protein urine, and more urine during night. Except the urinary system the whole system of the body can be influenced such as the digestive system and the circulation system.

Scientist said that some people do not suitable to use the herbs such as elder people and patients with diabetes and also some infant. For these people’s kidney function already have decreased so the toxin in the herbs can not be expelled from the body timely which increase the rate of getting kidney failure or other side effects.

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Factor of Eating Pain Killer Indiscriminately to Cause Nephritis

Pain killer is normal among us. Although majorities of pain killer are safe, we can’t take it at random. Eating pain killer randomly will cause nephritis. The factor of eating pain killer indiscriminately to cause nephritis are as follows:

1. Stimulate the gastrointestinal tract

Medicines such as aspirin and indometacin may stimulate gastric mucosa, causing severe gastrointestinal reaction, gastric ulcer and even gastrorrhagia, gastrobrosia. If you take calcium tablets at the time of taking pain killer, the stimulation will be largely increased.

2. Cause kidney damage

Pain killer will restrain the synthesis of prostaglandin, therefore the random use of pain killer may result in chronic tubulointerstitial nephritis, renal papillary necrosis and kidney dysfunction.

3. Induce cardiovascular disease

The US Food and Drug Administration once claimed that all of the non-steroid anti-inflammatory drugs have the risk of cardiovascular disease.

4. Cause hematological system disease

Long time use of pain killer may result in the decrease of leukocyte, causing aplastic anemia.

5. Produce psychological dependence

Long time use of pain killer will make patient have the psychological dependence and increase the anxious emotion. At last the atmosphere of “the more you take, the larger the dose is” and “ you can’t live without drugs” will appear.

Pain killer is one wonderful drug to relieve pain. But we shouldn’t take pain killer indiscriminately in case of nephritis.

If you have suffered from these kinds of uncomfort, and been diagnosed with nephritis, we're here to help. Email us: alisa1053360918@yahoo.com (Monday through Sunday) to make an appointment.

Is there other way to lower the creatinine except dialysis and kidney transplant?

Nowadays the most common ways to treat high creatinine are dialysis and kidney transplant. But the two ways have arose the doubt by the experts to lower the creatinine. There are a lot of difficulties to choose a proper kidney donor and the big expanse. What is more the high risk of the surgery and the protection after the surgery is very important. 

Compared with kidney transplant dialysis the living quality is higher. But it is a kind of treatment that can only take place the function of the kidney but not lower the high creatinine from the root causes.

After kidney transplant, the patients can avoid the suffering of dialysis and do not need to pay too much attention to the diet. And also some patients even can go back to work. But these things can not easily be achieved. All the efforts of the surgery will be in vain once things happen below.

● The precondition is the patients physical condition. In order to make the surgery success the doctor will check the patient’s condition for a long time and make sure it is under the condition to do the surgery. The quality of the donor is also important and the technique of the doctor is also essential.

● Rejection reaction is what the patients have to meet after the surgery. Some medicine is needed and also need to updated to increase the living rate of the kidney transplant patients. If the medicine can not work the patients need to do dialysis. What is more the more you use the rejection reaction medicine your body becomes more weak and the immune system will decrease.

● Many experts and patients try to find solutions to the traditional Chinese medicine. It shows that the traditional Chinese medicine can enlarge the blood vessel and increase the blood volume which can improve the condition of the kidney condition.

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The medicine for type 2 diabetes

Oral Medication

When people with type 2 diabetes are unable to control blood sugar sufficiently with diet and exercise, medication may be added. There are many types of diabetes pills available, and they are often used in combination. Some work by stimulating the pancreas to make more insulin, and others improve the effectiveness of insulin, or block the digestion of starches. Some medications used to treat type 2 diabetes also help inhibit the breakdown of insulin.

Insulin

Your doctor may prescribe insulin early on in your treatment and in combination with pills. Insulin can also used in people with type 2 diabetes who develop "beta-cell failure." This means the cells in the pancreas no longer produce insulin in response to high blood sugar levels. In this case, insulin therapy -- injections or an insulin pump -- must become part of the daily routine.

New drugs are available for people with type 2 diabetes. Pramlintide (Symlin), exenatide (Byetta), and liraglutide (Victoza) are non-insulin injectable drugs. Whereas insulin pulls glucose into the cells, these medications cause the body to release insulin to control blood sugar levels.

In a healthy person, insulin helps turn food into energy -- in an efficient manner. The stomach breaks down carbohydrates from food into sugars, including glucose. Glucose then enters the bloodstream, which stimulates the pancreas to release insulin in just the right amount. Insulin, a hormone, allows glucose to enter cells throughout the body, where it is used as fuel. Excess glucose is stored in the liver.
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Formation of the kidney stone

Form the causes of the kidney stone we know that preventing kidney stone we should change our eating habit. We need to change the thinking that pursuing the one single nutrition and some certain nutritions. In daily life we can not only eat one food or some kind of food and ignore other food.

We need to pay attention to our food and the diet should be variable. Even the healthy check showed that we lack some nutrition in our body it is not right to supply it much amount in one time. Because the human body can not absorb these nutritions in one time. The extra nutritions will be removed by kidney through urine which as a result will burden the kidney and the urine system. It is harmful to human body if not bring kidney stone.

After the patients are diagnosed kidney stone he should limit the food that can promote the forming of the stone. Kidney stone is a kind of urine stone which may forme in the hot summer. Because people sweat a lot in summer and in the same time with less liquid intake the urine volume will decrease. What is more in summer the sunshine is strong which can help the vitamin D combine with vitamin A and the combination can make the calcium increase so easy to form stone. In winter the weather is cold and the human urine volume will increase so the small stone will be removed by the urine. When the stone moving in the urine tract people will feel painful. So kidney stone often referred to form in summer but painful in winter.

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